Publications

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106. Mahmousianehkordi S, Maadooliat Mǂ, Schrodi SJǂ. (2024) GWID: An R package for genome-wide analysis of IBD data. Bioinformatics Adv vbae115. (ǂCorr Authors) Publication link

105. Hannah W, Nykamp K, Drumm M, Pramparo T, Steiner RD, Schrodi SJǂ. (2024) Using genomic databases to determine the frequency and population-based heterogeneity of autosomal recessive conditions. Genet Med Open 101881 (ǂCorr Author) Publication link

104. Liang H, Sedillo J, Schrodi SJǂ, Ikeda Aǂ. (2024) Structural variants in linkage disequilibrium with GWAS-significant SNPs. Heliyon 10(11):E32053; (ǂCorr Authors) Publication link

103. Sedillo JC, Badduke C, Schrodi SJ, Scaria V, Onat OE, Alfadhel M, Ober C, Steiner RD, Saba JD. (2024) Prevalence estimate of sphingosine phosphate lyase insufficiency syndrome in worldwide and select populations. Genet Med Open 100840 Publication link

102. Chen R, Bai J, Zhang D, Chen L, Zhou Y, Xia P, Li A, Gu Y, Cui L, Schrodi SJ, Yi X. (2023) Next-generation liquid biopsy elucidates cfDNA origins from organ delineation to cellular population granularity. Innov Life 1(3):100041. Commentary

101. Zhao J, Shi Y, Wei K, Jiang P, Xu L, Chang C, Xu L, Zheng Y, Shan Y, Liu J, Guo S, Schrodi SJ, Wang R, He D. (2023) Identification of immunological characterization and Anoikis-related molecular clusters in rheumatoid arthritis. Front Mol Biosci 1202371. Frontiers in Molecular Biosciences

100. Haas KM, McGregor MJ, Bouhaddou M, Polacco BJ, Kim E, Nguyen TT, Newton BW, Urbanowski M, Kim H, Williams MAP, Rezelj VV, Hardy A, Stevenson EJ, Sukerman E, Kim T, Penugonda S, Moreno E, Braberg H, Zhou Y, Metreveli G, Harjai B, Tummino TA, Melnk JE, Soucheray M, Batra J, Pache L, Martin-Sancho L, Carlson-Stevemer J, Jureka AS, Basler CF, Shokat KM, Shoichet BK, Shriver L, Johnson JR, Shaw ML, Chanda SK, Roden DM, Carter TC, Kottyan LC, Chisholm RL, Schrodi SJ, Albrecht RA, Vignuzzi M, Zuliani-Alvarez L, Swaney DL, Eckhardt M, Wolinsky SM, White KM, Hultquist JF, Kaake RM, Garcia-Sastre A, Krogan NJ. (2023) Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets. Nat Commun 14(1):6030. PMID: 37758692

99. Shan Y, Zhao J, Wei K, Jiang P, Xu L, Chang C, Xu L, Shi Y, Zheng Y, Bian Y, Zhou M, Schrodi SJ, Guo S, He D. (2023) A comprehensive review of Tripterygium wilfordii Hook. f. in the treatment of rheumatic and autoimmune diseases: bioactive compounds, mechanisms of action, and future directions. Front Pharmacol 14:1282610. Front Pharmacol

98. Verma A, Schrodi S, Bosco D, Ehret G, Keller M, Meier R. (2023) Single nucleotide polymorphisms associated with human islet insulin secretion. Transplantation 107:10S2 Transplantation

97. Zheng Y, Zhao J, Zhou M, Wei K, Jiang P, Xu L, Chang C, Shan Y, Xu L, Shi Y, Schrodi SJ, Guo S, He D. (2023) Role of signaling lymphocytic activation molecule family of receptors in the pathogenesis of rheumatoid arthritis: insights and application. Front Pharmacol 14:1306584. Front Pharmacol

96. Zhao M, Zhang RR, Chang C, Jin Y, Xu L, Guo S, Schrodi SJǂ, He Yǂ, He Dǂ. (2023) Whole-exome sequencing and genome-wide methylation profiling to Czech dysplasia in a Chinese pedigree. Front Med 10:1244888.

95. Zhang F, Zhang X, Zhang H, Lin D, Fan H, Guo S, An F, Zhao Y, Li J, Schrodi SJǂ, Zhang Dǂ. (2023) Pan-precancer and cancer DNA methylation profiles revealed significant tissue specificity of interrupted biological processes in tumorigenesis. Epigenetics 18(1):2231222. PMID: 37393582

94. Zhang H, Dong P, Fan H, Liang H, Zhang K, Zhao Y, Guo S, Schrodi SJ, Fan Y, Zhang D. (2023) Gene body hypomethylation of pyroptosis-related genes NLRP7, NLRP2, and NLRP3 facilitate non-invasive surveillance of hepatocellular carcinoma. Funct Integr Genomics 23(2):198.
PMID: 37273114

93. Li X, Fan H, Song X, Song B, Liu W, Dong R, Zhang H, Guo S, Liang H, Schrodi SJ, Fu X, Kaushal S, Ren Y, Zhang D. (2023) DNA methylome and transcriptome profiling reveal key electrophysiology and immune dysregulation in hypertrophic cardiomyopathy. Epigenetics 18(1):2195307. Epigenetics

92. Zheng Y, Zhao J, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2023) Role of the granzyme family in rheumatoid arthritis: Current insights and future perspectives. Front Immunol 14:684. (ǂCorr Authors) Front Immunol

91. Singhal P, Veturi Y, Dudek SM, Lucas A, Frase A, Schrodi SJ, Fasel D, Weng C, Pendergrass R, Schaid DJ, Kullo IJ, Dikilitas O, Sleiman PMA, Hakonarson H, Moore JH, Williams SM, Ritchie MD, Verma SS. (2023) Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets. Am J Hum Genet 110:575-591. American Journal of Human Genetics 110(4):575-591

90. Shan Y, Zhao J, Zheng Y, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2023) Understanding the function of the GABAergic system and its potential role in rheumatoid arthritis. Front Immunol 14:510. (ǂCorr Authors) Front Immunol

89. Zhao J, Xu L, Chang C, Jiang P, Wei K, Shi Y, Xu L, Zheng Y, Shan Y, Yanqin B, Li L, Guo S, Schrodi SJ, Wang R, He D. (2022) Circulating methylation level of HTR2A is associated with inflammation and disease activity in rheumatoid arthritis. Front Immunol. 13:1054451. PMID: 36561742

88. Zhang R, Jin Y, Chang C, Xu L, Bian Y, Shen Y, Sun Y, Sun S, Schrodi SJ, Guo S, He D. RNA-seq and network analysis reveals unique chemokine signatures in synovial tissue from rheumatoid arthritis. (2022) Front Med 9:799440. PMID: 35602512

87. Zhao J, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2022) Absent in melanoma 2 (AIM2) in rheumatoid arthritis: novel molecular insights and implications. Cell Mol Biol Lett 27(1):108. (ǂCorr Authors) PMID: 36476420

86. Zhao J, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2022) Cuproptosis and cuprotosis-related genes in rheumatoid arthritis: implication, prospects, and perspectives. Front Immunol 13:930278. (ǂCorr Authors) PMID: 35990673

85. Zhao J, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2022) Trends in the contribution of genetic susceptibility loci to hyperuricemia and gout and associated novel mechanisms. Front Cell Dev Biol 10:937855. (ǂCorr Authors) PMID: 35813212

84. Jiang P, Wei K, Chang C, Zhao J, Zhang RR, Xu L, Jin Y, Xu L, Shi Y, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2022) SFRP1 negatively modulates pyroptosis of fibroblast-like synoviocytes in rheumatoid arthritis. Front Immunol 13:903475. (ǂCorr Authors) PMID: 35795672

83. Zhao J, Wei K, Chang C, Xu L, Jiang P, Guo Sǂ, Schrodi SJǂ, He Dǂ (2022) DNA methylation of T lymphocytes as a therapeutic target: implications for rheumatoid arthritis etiology. Front Immunol 13:863703. (ǂCorr Authors) PMID: 35309322

82. Zhang Dǂ, Guo S, Schrodi SJǂ. (2021) Mechanisms of DNA methylation in virus-host interaction in hepatitis B infection: Pathogenesis and oncogenetic properties. Int J Mol Sci. 22(18):9858. (ǂCorr Authors) PMID: 34576022

81. Zhao J, Jiang P, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2021) Apoptosis, autophagy, NETosis, necroptosis, and pyroptosis mediated programmed cell death as targets for innovative therapy in rheumatoid arthritis. Front Immunol 12:809806. (ǂCorr Authors) PMID: 35003139

80. Agarwal G, Frink C, Hu B, Hu Z, Kim E, Lin H, Schrodi SJ, Keller M. (2021) Machine learning for glucose prediction to identify diabetes-related metabolic pathways. Project X Competition, University of Toronto

79. Zhao J, Guo Sǂ, Schrodi SJǂ, He Dǂ. (2021) Molecular and cellular heterogeneity in rheumatoid arthritis: mechanisms and clinical implications. Front Immunol 12:790122. (ǂCorr Authors) PMID: 34899757

78. Guo S, Jin Y, Zhou J, Zhu Q, Jiang T, Yanqin B, Zhang RR, Chang C, Xu L, Shen J, Zheng X, Shen Y, Qin Y, Chen J, Tang X, Cheng P, Ding Q, Zhang Y, Liu J, Cheng Q, Guo M, Liu Z, Qiu W, Sun Y, Shen Y, Nie H, Schrodi SJǂ, He Dǂ. (2021) MicroRNA variants and HLA-miRNA interactions are novel rheumatoid arthritis susceptibility factors. Front Genet 12:747274. (ǂCorr Authors) PMID: 34777472

77. Deng L, Xu J, Chen W, Guo S, Steiner RD, Chen Q, Cheng Z, Xu Y, Yao B, Li X, Wang X, Deng K, Schrodi SJ, Zhang Z, Xin H-B. (2021) Remediation of ABCG5-linked macrothrombocytopenia with Ezetimibe therapy. Front Genet 12:769699. PMID: 34880906

76. Zhang H, Dong P, Guo S, Tao C, Zhao W, Wang J, Cheung R, Villanueva A, Ding H, Schrodi SJǂ, Zhang Dǂ, Zeng Cǂ. (2020) Long-region hypomethylation in HBV integration regions enhance HCC non-invasive surveillance by low-pass whole genome-wide bisulfite sequencing. BMC Medicine 18(1):200 (ǂCorr Authors) PMID: 32741373

75. Guo S, Liu J, Jiang T, Lee D, Wang R, Zhou X, Jin Y, Shen Y, Wang Y, Bai F, Ding Q, Wang G, Zhang Y, Zhou X, Schrodi SJ, He D. (2019) (5R)-5-Hydroxytriptolide (LLDT-8) induces substantial epigenetic mediated immune response network changes in fibroblast-like synoviocytes from rheumatoid arthritis patients. Sci Rep 9:11155. PMID: 31371761

74. Mergaert AM, Bawadekar M, Nguyen TQ, Massarenti L, Holmes CL, Rebernick R, Schrodi SJ, Shelef MA. (2019) Reduced anti-histone antibodies and increased risk of rheumatoid arthritis associated with a single nucleotide polymorphism in PADI4 in North Americans. Int J Mol Sci 20(12):3093. PMID: 31242568

73. Guo S, Jiang S, Epperla N, Ma Y, Maadooliat M, Ye Z, Olson B, Wang M, Kitchner T, Joyce J, Strenn R, Mazza JJ, Meece JK, Wu W, Jin L, Smith JA, Wang Jǂ, Schrodi SJǂ. (2019) A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron metabolism gene. Blood 133(17):1888-1898. (ǂCorr Authors) PMID: 30814063

72. Bansal NK, Maadooliat M, Schrodi SJ. (2018) Empirical Bayesian approach to testing multiple hypotheses with separate priors for left and right alternatives. Stat Appl Genet Mol Biol 17(4):20180002. PMID: 29975669

71. Liu Y, Ye Z, Li X, Anderson JL, Khan M, DaSilva D, Baron M, Wilson D, Bocoun V, Ivacic LC, Schrodi SJ, Smith JA. (2017) Genetic and functional associations with decreased anti-inflammatory Tumor Necrosis Factor Alpha Induced Protein 3 in macrophages from subjects with axial spondyloarthritis. Front Immunol 8:860. PMID: 28791018

70. Schrodi SJǂ. (2017) The impact of diagnostic code misclassification on optimizing the experimental design of genetic association studies. J Healthc Eng 2017:7653071. (ǂCorr Author) PMID: 29181145

69. Schotthoefer AM, Schrodi SJ, Meece JK, Fritsche TR, Shukla SK. (2017) Pro-inflammatory immune responses are linked to clinical signs and symptoms in human anaplasmosis. PLoS ONE 12(6): e0179655. PMID: 28628633

68. Schrodi SJǂ (2017) Postmortem Genetic Testing for Sudden Unexpected Death. JAMA 317(3):320-321. (ǂCorr Author) PMID: 28114545

67. Maadooliat M, Bansal NK, Upadhya J, Farazi MR, Li X, He M, Hebbring SJ, Ye Z, Schrodi SJǂ. (2016) The decay of disease association with declining linkage disequilibrium: A fine mapping theorem. Front Genet 7:217. (ǂCorr Author) PMID: 28018425

66. Schrodi SJǂ. (2016) Reflections on the field of human genetics: A call for increased disease genetics theory. Front Genet 7:106. (ǂCorr Author) PMID: 27375680

65. Carter TC, Rein D, Padberg I, Peter E, Rennefahrt U, David DE, McManus V, Stefanski E, Martin S, Schatz P, Schrodi SJǂ. (2016) Validation of a metabolite panel for early diagnosis of type 2 diabetes. Metabolism 65:1399-1408. (ǂCorr Author) PMID: 27506746

64. Schrodi SJǂ. (2016) The use of multiplicity corrections, order statistics and generalized family-wise statistics in genome-wide studies. PLoS ONE 11(4):e0154472. (ǂCorr Author) PMID: 27128491

63. Tokarz SA, DeValk J, Luo W, Pattnaik BR, Schrodi SJ, Pillers DM. (2016) Toll-like receptor genotype may influence cell line innate-immunity phenotype. Mol Genet Metab 118(3):147-152. PMID: 27324283

62. Brilliant MH, Vaziri K, Connor TB, Schwatrz SG, Carroll JJ, McCarty CA, Schrodi SJ, Hebbring SJ, Kishor KS, Flynn HW, Moshfeghi AA, Moshfeghi DM, Fini ME, McKay BS. (2016) Mining retrospective data for virtual prospective drug repurposing: L-DOPA and Age-related Macular Degeneration. Am J Med 129(3):292-298. PMID: 26524704

61. Shukla SK, Cook D, Meyer J, Vernon SD, Le T, Clevidence D, Robertson CE, Schrodi SJ, Yale S, Frank DN. (2015) Changes in gut and plasma microbiome following exercise challenge in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). PLoS ONE 10(12):e0145453. PMID: 26683192

60. Schrodi SJǂ and Jones HB. (2015) Calculating exact P-values from the McNemar Transmission/Disequilibrium Test Statistic. J Invest Genomics 2(4):00032. (ǂCorr Author) DOI:10.15406/JIG.2015.02.00032

59. Shukla SK, Rose W, Schrodi SJ. (2015) Complex host genetic susceptibility to Staphylococcus aureus infections. Trends Microbiol. 23(9):529-536. PMID: 26112911

58. Schrodi SJǂ, DeBarber A, He M, Ye Z, Peissig P, Van Wormer JJ, Haws R, Brilliant MH, Steiner RD. (2015) Prevalence estimation for monogenic autosomal recessive diseases using population-based genetic data. Hum Genet. 134(6):659-669. (ǂCorr Author) PMID: 25893794

57. O’Brien SE, Schrodi SJ, Ye Z, Brilliant MH, Virani SS, Brautbar A. (2015) Differential lipid response to statins is associated with variants in the BUD13-APOA5 gene region. J Cardiovasc Pharmacol. 66(2):183-188. PMID: 25900265

56. He M, Person TN, Hebbring SJ, Heinzen E, Ye Z, Schrodi SJ, McPherson EW, Lin SM, Peissig PL, Brilliant MH, O’Rawe J, Robison RJ, Lyon GJ, Wang K. (2015) SeqHBase: a big data toolset for family based sequencing data analysis. J Med Genet 52(4): 282-288. PMID: 25587064

55. Ye Z, Mayer J, Ivacic L, Zhou Z, He M, Schrodi SJ, Page D, Brilliant MH, Hebbring SJ.(2015) Phenotype-wide association studies (PheWASs) for functional variants. Eur J Hum Genet 23(4):523-529. PMID: 25074467

54. Munro SA, Lund SP, Pine PS,…Schrodi SJ,…, Salit ML. (2014) Assessing technical performance in differential gene expression experiments with external spike-in RNA control ratio mixtures. NIST Publications. National Institute of Standards and Technology Publication

53. Mayer J, Kitchner T, Ye Z, Zhou Z, He M, Schrodi SJ, Hebbring SJ. (2014) Use of an electronic medical record to create the marshfield clinic twin/multiple birth cohort. Genet Epidemiol. 38(8):692-698. PMID: 25250975

52. Schrodi SJǂ, Mukherjee S, Shan Y, Tromp G, Sninsky JJ, Callear AP, Carter TC, Ye Z, Haines JL, Brilliant MH, Crane PK, Smelser DT, Elston RC, Weeks DE. (2014) Genetic-based prediction of disease traits: prediction is very difficult, especially about the future. Front Genet. 5:162. (ǂCorr Author) PMID: 24917882

51. Schrodi SJǂ, Rein D, Carter T, Martin S. (2014) Outperforming fasting plasma glucose, metabolite biomarkers, and their role in diabetes. Diabetes 63:A616. (ǂCorr Author)

50. Ye Z, Vasco DA, Carter TC, Brilliant MH, Schrodi SJ, Shukla SK.(2014) Genome wide association study of SNP-, gene-, and pathway-based approaches to identify genes influencing susceptibility to Staphylococcus aureus infections. Front Genet. 5:125. PMID: 24847357

49. Hebbring SJ, Schrodi SJ, Ye Z, Zhou Z, Page D, Brilliant MH. (2013) A PheWAS approach in studying HLA-DRB1*1501. Genes Immun. 14(3):187-191. PMID: 23392276

48. Vasco DA, Ye Z, Lee D, Schodi SJǂ, Lin S (2012) Population genetic inference for a whole genome Korean sample. CAMDA 2012 (ǂCorr Author) CAMDA 2012

47. Hebbring SJ, Slager SL, Epperla N, Mazza JJ, Ye Z, Zhou Z, Achenbach SJ, Vasco DA, Call TG, Rabe KG, Kay NE, Caporaso NE, Lanasa MC, Camp NJ, Strom SS, Goldin LR, Cerhan JR, Brilliant MH, Schrodi SJǂ. (2013) Genetic evidence of PTPN22 effects on chronic lymphocytic leukemia. Blood 121(1):237-238. (ǂCorr Author) PMID: 23287625

46. Tsoi LC, Spain SL, Knight J, Ellinghaus E,…,Schrodi SJ,.. Barker JN, Abecasis GR, Elder JT, Trembath RC. (2012) Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat Genet. 44(12):1341-1348. PMID: 23143594

45. Feng BJ, Sun LD, Soltani-Arabshahi R, Bowcock AM, Nair RP, Stuart P, Elder JT, Schrodi SJ, Begovich AB, Abecasis GR, Zhang XJ, Callis-Duffin KP, Krueger GG, Goldgar DE. (2009) Multiple loci within the major histocompatibility complex confer risk of psoriasis. PLoS Genet 5(8):e1000606. PMID: 19680446

44. Schrodi SJǂ, Li Y, Chang M, Garcia VE, Callis Duffin K, Nair RP, Bowcock AM, Elder JT, Krueger GG, Rowland CM. (2009) Trait prediction using multi-locus information: psoriasis as a model for complex disease prognostics. Genet Epidemiol 33:752. (ǂCorr Author)

43. Duffin KC, Freeny IC, Schrodi SJ, Wong B, Feng BJ, Soltani-Arabshahi R, Rakkhit T, Goldgar DE, Krueger GG. (2009) Association between IL13 polymorphisms and psoriatic arthritis is modified by smoking. J Invest Dermatol. 129(12):2777-2783. PMID: 19554022

42. Li Y, Brambha K, Christopherson CD, Kwok SY, Chang M, Catanese J, Schrodi SJ, Ross DA, Campos GM, Monot A, Wright TL, Layden TL, Cooper C, Shiffman ML, Cheung R, Friedman SL, Sninsky J, Still CD, Bass NM, Gerhard GS. (2009) A common, functional polymorphism in DDX5 is associated with cirrhosis in chronic hepatitis C and NAFLD patients. Hepatology 50:389.

41. Schrodi SJǂ, Garcia VE, Rowland CM (2009) A fine mapping theorem to refine results from association genetic studies. Am Soc Hum Genet 2009. ASHG link (ǂCorr Author)

40. Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, Gudjonsson JE, Li Y, Tejasvi T, Feng BJ, Ruether A, Schreiber S, Weichenthal M, Gladman D, Rahman P, Schrodi SJ, Prahalad S, Guthery SL, Fischer J, Liao W, Kwok PY, Menter A, Lathrop GM, Wise CA, Begovich AB, Voorhees JJ, Elder JT, Krueger GG, Bowcock AM, Abecasis GR; Collaborative Association Study of Psoriasis. (2009) Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet. 41(2):199-204. PMID: 19169254

39. Bambha K, Abar O, Chang M, Schrodi SJ, Ross DA, Catanese J, Lagier RJ, Rowland CM, Merriman RB, Aouizerat BE, Sninsky J, Bass NM. (2008) Common genetic polymorphisms associated with advanced fibrosis in patients with chronic hepatitis C are associated with nonalcoholic steatohepatitis and cirrhosis in patients with nonalcoholic fatty liver disease. (2008) Hepatology 48(4):815A.

38. Li Y, Liao W, Chang M, Schrodi SJ, Bui N, Catanese JJ, Poon A, Matsunami N, Callis-Duffin KP, Leppert MF, Bowcock AM, Kwok PY, Krueger GG, Begovich AB. (2009) Further genetic evidence for three psoriasis-risk genes: ADAM33, CDKAL1, and PTPN22. J Invest Dermatol. 129(3):629-634. PMID: 18923449

37. Schrodi SJǂ (2008) Genome-wide association scan in psoriasis: new insights into chronic inflammatory disease. Expert Rev Clin Immunol. 4(5):565-571. (ǂCorr Author) PMID: 20476959

36. Garcia VE, Chang M, Brandon R, Li Y, Matsunami N, Callis-Duffin KP, Civello D, Rowland CM, Bui N, Catanese JJ, Krueger GG, Leppert MF, Begovich AB, Schrodi SJ.ǂ (2008) Detailed genetic characterization of the interleukin-23 receptor in psoriasis. Genes Immun. 9(6):546-555. (ǂCorr Author) PMID: 18650833

35. Chang M, Rowland CM, Garcia VE, Schrodi SJ, Catanese JJ, van der Helm-van Mil AH, Ardlie KG, Amos CI, Criswell LA, Kastner DL, Gregersen PK, Kurreeman FA, Toes RE, Huizinga TW, Seldin MF, Begovich AB. (2008) A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2. PLoS Genet. 4(6):e1000107. PMID: 18648537

34. Li Y, Rowland C, Xiromerisiou G, Lagier RJ, Schrodi SJ, Dradiotis E, Ross D, Bui N, Catanese J, Aggelakis K, Grupe A, Hadjigeorgiou G. (2008) Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson’s disease. PLoS ONE 3(7):e2707. PMID: 18628988

33. Li Y, Chang M, Schrodi SJ, Callis-Duffin KP, Matsunami N, Civello D, Bui N, Catanese JJ, Leppert MF, Krueger GG, Begovich AB. (2008) The 5q31 variants associated with psoriasis and Crohn’s disease are distinct. Hum Mol Genet. 17(19):2978-2985. PMID: 18614543

32. Chang M, Saiki RK, Cantanese JJ, Lew D, van der Helm-van Mil AH, Toes RE, Huizinga TW, Ardlie KG, Criswell LA, Seldin MF, Amos CI, Kastner DL, Gregersen PK, Schrodi SJ, Begovich AB. (2008) The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritis. Arthritis Rheum. 58(6):1877-1881. PMID: 18512797

31. Freery IC, Wong B, Schrodi SJ, Begovich AB, Duffin KP, Krueger GG. (2008) Phenotypic and genotypic profile of psoriatic patients with asthma. J Invest Dermatol. 128: S15.

30. Kurreeman F, Padyukov L, Marques R, Schrodi S, Seddighzadeh M, Stoeken-Rijsbergen G, Van der Helm-Van Mil A, Verduyn W, Housing-Duistermaat J, Alsfredsson L, Begovich A, Petit-Texeira E, Cornelis F, Klareskog L, Toes R. (2008) Association and linkage of the TRAF1/C5 region with specific subsets of rheumatoid arthritis. Annals of the Rheumatic Diseases 67:A45.

29. Chang M, Li Y, Yan C, Callis-Duffin KP, Matsunami N, Garcia VE, Cargill M, Civello D, Bui N, Catanese JJ, Leppert MF, Krueger GG, Begovich AB, Schrodi SJ. (2008) Variants in the 5q31 cytokine gene cluster are associated with psoriasis. Genes Immun. 9(2):176-181. PMID: 18075513

28. Kurreeman FA, Padyukov L, Marques RB, Schrodi SJ, Seddighzadeh M, Stoeken-Rijsbergen G, van der Helm-van Mil AH, Allaart CF, Verduyn W, Houwing-Duistermaat J, Alfredsson L, Begovich AB, Klareskog L, Huizinga TW, Toes RE. (2007) A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis. PLoS Med. 4(9):e278. PMID: 17880261

27. Schrodi SJǂ, Chang M, Ardlie KG, Amos CI, Criswell LA, Kastner DL, Gregersen PK, Seldin MF, Toes REM, Huizinga TWJ, Begovich AB. (2007) A large-scale rheumatoid arthritis genetic study identifies TRAF1 variants on chr 9q33.2. Am S Hum Genet ASHG (ǂCorr Author)

26. Schrodi SJǂ, Chang M, Matsunami N, Leppert MF, Krueger GG, Begovich AB (2007) Detailed genetic characterization of the psoriasis-associated gene IL23R. J Invest Dermatol 127:S18. (ǂCorr Author)

25. Beasley E, Schrodi SJ, Chang M, Callis KP, Leppert MF, Krueger GG, Begovich AB (2007) Detailed genetic characterization of the psoriasis-associated gene IL12B to further define the causal variant(s). J Invest Dermatol 127:S15.

24. Begovich AB, Chang M, Schrodi SJ. (2007) Meta-analysis evidence of a differential risk of the FCRL3 -169T –>C polymorphism in white and East Asian rheumatoid arthritis patients. Arthritis Rheum. 56(9):3168-3171. PMID: 17763442

23. Cargill M*, Schrodi SJ*, Chang M, Garcia VE, Brandon R, Callis KP, Matsunami N, Ardlie KG, Civello D, Catanese JJ, Leong DU, Panko JM, McAllister LB, Hansen CB, Papenfuss J, Prescott SM, White TJ, Leppert MF, Krueger GG, Begovich AB. (2007) A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am J Hum Genet. 80(2):273-290. (*Co-Lead Author) PMID: 17236132

22. Begovich A, Chang M, Leppert M, Schrodi S, Krueger G. (2007) Characterization of psoriasis-associated IL12B and IL23R genes. Clinical Immunol 123:S126.

21. Schrodi SJǂ, Garcia VE, Rowland C, Jones HB. (2007) Pairwise linkage disequilibrium under disease models. Eur J Hum Genet. 15(2):212-220. (ǂCorr Author) PMID: 17106449

20. Li Y, Schrodi S, Rowland C, Tacey K, Catanese J, Grupe A. (2006) Genetic evidence for ubiquitin-specific proteases USP24 and USP40 as candidate genes for late-onset Parkinson disease. Hum Mutat. 27(10): 1017-1023. PMID: 16917932

19. Huang H, Shiffman ML, Cheung RC, Layden TJ, Friedman S, Abar OT, Yee L, Chokkalingam AP, Schrodi SJ, Chan J, Catanese JJ, Leong DU, Ross D, Hu X, Monto A, McAllister LB, Broder S, White T, Sninsky JJ, Wright TL. (2006) Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C. Gastroenterology 130(6):1679-1687. PMID: 16697732

18. Panko J, Wong B, Schrodi S, Callis K, Cargill M, Krueger G. (2006) Characterizing susceptibility to phenotypic variations of psoriasis by comparing alleleic association signals on PSORS loci chromosomes. J Invest Dermatol 126:84.

17. Li Y, Rowland C, Schrodi S, Laird W, Tacey K, Ross D, Leong D, Catanese J, Sninsky J, Grupe A. (2006) A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan. Am J Hum Genet. 78(6):1090-1092. PMID: 16685663

16. Begovich AB, Schrodi SJ, Leppert M, Krueger G, Cargill M. (2006) A genome-wide association study of putative functional SNPs leads to the identification of two psoriasis loci–IL12B and IL23R–in 3 independent white North American sample sets. Am J Hum Genet A163.

15. Panko J, Schrodi S, Wong B, Callis K, Matsunami N, Cargill MA, Krueger GG. (2006) Characterizing susceptibility to phenotypic variations of psoriasis by comparing allelic association signals on chromosome 6. British J Dermatology 154(1).

14. Schrodi SJǂ (2005) A probabilistic approach to large-scale association scans: a semi-Bayesian method to detect disease-predisposing alleles. Stat Appl Genet Mol Biol 4:Article 31. (ǂCorr Author) PMID: 16646850

13. Huang H, Wright TL, Tuason O, Yee L, Chokkalingam AP, Schrodi SJ, Chan J, Catanese J, Leong DU, Emerson R, Monto A, McAllister LB, Layden TJ, Cheung RC, Sninsky JJ, Shiffman ML. (2005) Association of fibrosis risk in HCV patients with a missense single nucleotide polymorphism in a gene encoding carnitine palmitoyl-transferase 1A (CPT1A). J Hepatology 42:22.

12. Huang H, Merriman RB, Chokkalingam AP, Tuason O, Schrodi SJ, Aouizerat BE, Chan J, Catanese JJ, Leong DU, McAllister LB, Sninsky JJ, Bass NM. (2005) Novel genetic markers associated with risk of non-alcoholic steatohepatitis in patients with non-alcoholic fatty liver diseases. Gastroenterology 128:A694.

11. Carlton VE, Hu X, Chokkalingam AP, Schrodi SJ, Brandon R, Alexander HC, Chang M, Catanese JJ, Leong DU, Ardlie KG, Kastner DL, Seldin MF, Criswell LA, Gregersen PK, Beasley E, Thomson G, Amos CI, Begovich AB. (2005) PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritis. Am J Hum Genet. 77(4):567-581. PMID: 16175503

10. Huang HJ, Shiffman ML, Tuason O, Yee L, Schrodi SJ, Chokkalingam AP, Chan J, Catanese JJ, Leong DU, Emerson R, Monto A, McAllister LB, Layden TJ, Cheung RC, Sninsky JJ, Wright TL. (2004) Identification of novel genetic markers associated with fibrosis progression risk in HCV patients from a genomic scan of putative functional polymorphisms. Hepatology 40(4):230.

9. Li Y, Nowotny P, Holmans P, Smemo S, Kauwe JS, Hinrichs AL, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Chan J, Cravchik A, Ross D, Lau K, Kwok S, Chang SY, Catanese J, Sninsky J, White TJ, Hardy J, Powell J, Lovestone S, Morris JC, Thal L, Owen M, Williams J, Goate A, Grupe A. (2004) Association of late-onset Alzheimer’s disease with genetic variation in multiple members of the GAPD gene family. Proc Natl Acad Sci USA 101(44):15688-15693. PMID: 15507493

8. Doil L, Tacey K, Nowotny P, van Luchene R, Li Y, Holmans P, Smemo S, Garcia V, Rowland C, Schrodi S, Leong D, Gogic G, Cravchik A, Ross D, Lau K, Catanese J, Sninsky J, White T, Hardy J, Powell J, Lovestone S, Thal L, Owen M, Williams J, Goate A, Grupe A. (2004) A systematic scan of chromosome 10 single nucleotide polymorphisms identifies novel candidate genes showing strong association to Alzheimer’s disease. Neurobiology of Aging 25:S505.

7. Li Y, Nowotny P, Holmans P, Smemo S, Kawe K, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Chan J, Lau K, Chang S-Y, Catanese J, Sninsky J, White T, Hardy J, Lovestone S, Thal L, Owen M, Williams J, Goate A, Grupe A. (2004) Association of late onset Alzheimer’s disease with genetic variation in multiple members of a gene family involved in neuronal apoptosis. Neurobiol Aging 25:S486.

6. Hu X, Schrodi SJ, Ross DA, Cargill M. (2004) Selecting tagging SNPs for association studies using power calculations from genotype data. Hum Hered. 57(3):156-170. PMID: 15297809

5. Carlton VEH, Schrodi SJ, Hu XL, Garcia VE, Alexander HC, Chokkalingam A, Huang QQ, Brandon RC, Chang M, Ardlie KG, Catanese JJ, Leong DU, Criswell LA, Seldin MF, Kastner DL, Gregersen PK, Beasley EM, Sninsky JJ, Amos CI, Begovich AB. (2004) Protein tyrosine phosphatase PTPN22 and rheumatoid arthritis. Arthritis and Rheumatism 50(9):S672.

4. Li Y, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, Schrodi S, Leong D, Lau K, Catanese J, Sninsky J, Nowotny P, Holmans P, Hardy J, Powell J, Lovestone S, Thal L, Owen M, Williams J, Goate A, Grupe A. (2004) Association of ABCA1 with late-onset Alzheimer’s disease is not observed in a case-control study. Neurosci Lett. 366(3):268-271. PMID: 15288432

3. Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, Ardlie KG, Huang Q, Smith AM, Spoerke JM, Conn MT, Chang M, Chang SY, Saiki RK, Catanese JJ, Leong DU, Garcia VE, McAllister LB, Jeffery DA, Lee AT, Batliwalla F, Remmers E, Criswell LA, Seldin MF, Kastner DL, Amos CI, Sninsky JJ, Gregersen PK. (2004) A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet. 75(2):330-337. PMID: 15208781

2. Cargill M, Clark A, Glanowski S, Nielsen R, Tanenbaum D, Thomas P, Duff J, Gire H, Ferriera A, Civello D, Evans C, Fosler C, Forbes C, Hannenhalli S, Kejariwal A, Levy S, Rydland M, Schrodi S, Sninsky J, Adams M. (2003) Genome-wide comparative sequence analysis between human, mouse, and chimpanzee identifies human genes under positive selection. Am J Hum Genet 73(5):430. American Journal of Human Genetics 73(5): 430

1. Schrodi SJ. (2001) Mathematical models in population genetics, molecular evolution and genomics. UMI Dissertation Services. Ann Arbor, MI, USA. Dissertation

BOOK CHAPTER

Schrodi SJ. (2012) Oral Health in the Age of Genome-Wide Studies. In: Integration of Medical and Dental Care and Patient Data: Progress in Health Care Informatics. Eds: Powell, Din, Acharya, Torres-Urquidy. United Kingdom: Springer London. Integration of Medical and Dental Care and Patient Data

TEXTBOOK (under contract, in-progress)

Schrodi SJ. An Introduction to Human Genetics Fundamentals. Springer Nature Switzerland AG